White Blood Cell Differential Count
White Blood Cell Differential Count (Differential, Diff)
Kiat membaca Hasil Laboratorium Darah Part III
Postingan kali ini adalah bagian terakhir dari postingan-postingan terdahulu.
Pemeriksaan Darah Lengkap
Darah lengkap (Complete Blood Count/CBC) adalah pemeriksaan untuk menilai jumlah sel darah dan kadar hemoglobin. Saat ini pemeriksaan darah lengkap sudah menggunakan alat penghitung sel darah otomatis atau disebut haematology analyzer yang mampu menghitung sel-sel darah dengan waktu yang cepat dan akurat. Pemeriksaan darah ini juga sering disebut sebagai pemeriksaan darah rutin. Beberapa parameter yang diperiksa adalah :
Pemeriksaan Sel Darah Putih (Lekosit)
Jumlah sel darah putih (lekosit) atau White Blood Cell (WBC). Normalnya, jumlah lekosit dalam darah adalah 4,0 – 11,0 x10^3/mmk (millimeter kubik) darah. Lekosit yang tinggi dapat dijumpai pada infeksi bakterial, tumor, luka bakar, leukemia, dsb. Jumlah lekosit dapat menurun pada penyakit sumsum tulang (misalnya pada anemia aplastik, mielofibrosis, infiltrasi neoplasma, dsb), inveksi virus (demam berdarah dengue, campak, HIV, dsb), pengaruh obat-obatan (misalnya obat anti kanker), dan sebagainya.
Hitung jenis lekosit atau differential count. Pem
The white blood cell differential count determines the number of each type of white blood cell, present in the blood.
It can be expressed as a percentage (relative numbers of each type of WBC in relationship to the total) or as an absolute value (percentage x total WBC). Of these, the absolute value is much more important than the relative value.
There are five basic white blood cell types:
Neutrophils
Eosinophils
Basophils
Lymphocytes
Monocytes
Each WBC cell type has its' own unique features.
________________________________________
Neutrophils (Segmented Neutrophils, Segs, Polymorphonucleocytes, Polymorphonuclear Neutrophils, Polys, PMNs)
These are the most common of the WBCs and serve as the primary defense against infection. The typical response to infection or serious injury is an increased production of neutrophils.
________________________________________
Bands/Stabs
Early in the response to infection, immature forms of neutrophils will be seen. These are call Stab or Band cells. The presence of these immature cells is called a "shift to the left" and can be the earliest sign of a WBC response, even before the WBC becomes elevated.
________________________________________
Eosinophils (Eos)
These cells play a role in allergic disorders and in combating parasitic infections.
Elevations in eosinophil counts are associated with:
Allergic reactions
Parasite infections
Chronic skin infections
Some cancers
Decreases in eosinophil counts are associated with:
Stress
Steroid exposure
Anything that may suppress WBC production generally
________________________________________
Basophils (Baso's)
These cells can digest bacteria and other foreign bodies (phagocytosis) and also have some role in allergic reactions.
Elevations in basophil counts are associated with:
Some cancers
Some allergic reactions
Some infections
Radiation exposure
Diminished basophil counts are associated with:
Stress reactions
Some allergic reactions
Hyperthyroidism
Prolonged steroid exposure
________________________________________
Monocytes (Mono's)
These cells respond to inflammation, infection and foreign bodies by ingesting and digesting the foreign material.
Increased monocyte counts are associated with:
Recovery from an acute infection
Viral illness
Parasitic infections
Collagen disease
Some cancers
Decreased monocyte counts are associated with:
HIV infection
Rheumatoid arthritis
Steroid exposure
Some cancers
________________________________________
Lymphocytes (Lymphs)
These cells play both an immediate and delayed role in response to infection or inflammation.
Increased numbers of lymphocytes are seen in:
Most viral infections
Some bacterial infections
Some cancers
Graves' disease
Decreased numbers of lymphocytes are seen in:
Steroid exposure
Some cancers
Immunodeficiency
Renal failure
Lupus
Kiat membaca Hasil Laboratorium Darah Part III
Postingan kali ini adalah bagian terakhir dari postingan-postingan terdahulu.
Pemeriksaan Darah Lengkap
Darah lengkap (Complete Blood Count/CBC) adalah pemeriksaan untuk menilai jumlah sel darah dan kadar hemoglobin. Saat ini pemeriksaan darah lengkap sudah menggunakan alat penghitung sel darah otomatis atau disebut haematology analyzer yang mampu menghitung sel-sel darah dengan waktu yang cepat dan akurat. Pemeriksaan darah ini juga sering disebut sebagai pemeriksaan darah rutin. Beberapa parameter yang diperiksa adalah :
Pemeriksaan Sel Darah Putih (Lekosit)
Jumlah sel darah putih (lekosit) atau White Blood Cell (WBC). Normalnya, jumlah lekosit dalam darah adalah 4,0 – 11,0 x10^3/mmk (millimeter kubik) darah. Lekosit yang tinggi dapat dijumpai pada infeksi bakterial, tumor, luka bakar, leukemia, dsb. Jumlah lekosit dapat menurun pada penyakit sumsum tulang (misalnya pada anemia aplastik, mielofibrosis, infiltrasi neoplasma, dsb), inveksi virus (demam berdarah dengue, campak, HIV, dsb), pengaruh obat-obatan (misalnya obat anti kanker), dan sebagainya.
Hitung jenis lekosit atau differential count. Pem
The white blood cell differential count determines the number of each type of white blood cell, present in the blood.
It can be expressed as a percentage (relative numbers of each type of WBC in relationship to the total) or as an absolute value (percentage x total WBC). Of these, the absolute value is much more important than the relative value.
There are five basic white blood cell types:
Neutrophils
Eosinophils
Basophils
Lymphocytes
Monocytes
Each WBC cell type has its' own unique features.
________________________________________
Neutrophils (Segmented Neutrophils, Segs, Polymorphonucleocytes, Polymorphonuclear Neutrophils, Polys, PMNs)
These are the most common of the WBCs and serve as the primary defense against infection. The typical response to infection or serious injury is an increased production of neutrophils.
________________________________________
Bands/Stabs
Early in the response to infection, immature forms of neutrophils will be seen. These are call Stab or Band cells. The presence of these immature cells is called a "shift to the left" and can be the earliest sign of a WBC response, even before the WBC becomes elevated.
________________________________________
Eosinophils (Eos)
These cells play a role in allergic disorders and in combating parasitic infections.
Elevations in eosinophil counts are associated with:
Allergic reactions
Parasite infections
Chronic skin infections
Some cancers
Decreases in eosinophil counts are associated with:
Stress
Steroid exposure
Anything that may suppress WBC production generally
________________________________________
Basophils (Baso's)
These cells can digest bacteria and other foreign bodies (phagocytosis) and also have some role in allergic reactions.
Elevations in basophil counts are associated with:
Some cancers
Some allergic reactions
Some infections
Radiation exposure
Diminished basophil counts are associated with:
Stress reactions
Some allergic reactions
Hyperthyroidism
Prolonged steroid exposure
________________________________________
Monocytes (Mono's)
These cells respond to inflammation, infection and foreign bodies by ingesting and digesting the foreign material.
Increased monocyte counts are associated with:
Recovery from an acute infection
Viral illness
Parasitic infections
Collagen disease
Some cancers
Decreased monocyte counts are associated with:
HIV infection
Rheumatoid arthritis
Steroid exposure
Some cancers
________________________________________
Lymphocytes (Lymphs)
These cells play both an immediate and delayed role in response to infection or inflammation.
Increased numbers of lymphocytes are seen in:
Most viral infections
Some bacterial infections
Some cancers
Graves' disease
Decreased numbers of lymphocytes are seen in:
Steroid exposure
Some cancers
Immunodeficiency
Renal failure
Lupus
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